Rheumatoid Ahritis is best diagnosed by

Answer is A (Anti-CCP Antibodies): 'Anti CCP antibodies are the most specific blood test for rheumatoid ahritis (specificity -95%)' - CMDT 09/727 Anti-cyclic citrullinated peptide (anti-CCP) antibody testing is paicularly useful in the diagnosis of rheumatoid ahritis, with high specificity, presence early in the disease process, and ability to identify patients who are likely to have severe disease and irreversible damage. Anti-CCP antibodies have not been found at a significant frequency in other diseases to date, and are more specific than rheumatoid factor for detecting rheumatoid ahritis.