Which of these are associated with increased risk of colorectal Ca -a) More intake of animal fatb) Aspirinc) Ulcerative colitisd) Amoebic colitise) Polyps

Risk factors for Colon cancer Dietay factures - explainaed in previous quetion Hereditary factors Polyposis coli  Nonopolyposis herditary colon cancer ( also known as Lynch syndrome) Inflammatory bowel disease - Long standing IBD increases the risk - Risk is more with ulcerative colitis than crohn's disese. - Risk increases with the duration and extent of colitis. 4. Streptococcus bovis bacteremia Individuals who develop endocarditis or septicemia from this bacteria, have a high incidence of occult colorectal tumors and passibly upper GI cancers also. 5. Other Risk factors (a) Ureterosiginoidostomy (b) Cigarette smoking - is linked to the development of colorectal adenomas , particularly after >35 yrs of use. (c) Acromegaly (d) Pelvic irradiation Aspirin & other NSAIDs use has been foud to have a protective effect (Chemopervention) Other substance found to have chemoprentive action are → Oral folic acid supplementation, Oral calcium supplementation, Estrogen replacement therapy.