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Microbiology General 2d9e4e4f

An 18 year old male presented with acute onset descending paralysis of 3 days duration. There is also a history of blurring of vision for the same duration. On examination, the patient has quadriparesis with areflexia. Both the pupils are non-reactive. The most probable diagnosis is:

A
Poliomyelitis
B
Botulism
C
Diphtheria
D
Porphyria
High-Yield Explanation
Diagnosis of botulism should be considered in patient with symmetric descending paralysis with bilateral cranial neuropathies in addition of following features: Absent fever Patient remains responsive Heart rate normal or slow Sensory deficit doesn’t occur except for blurred vision. Remember: Neurologic signs and symptom of botulism: Dysphagia Dry mouth Diplopia Dysarthria Upper limb weakness Lower limb weakness Blurred vision Dyspnea

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