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Pharmacology General 2d929b70

The antiepileptic drug which does not produce enzyme induction is -

A
Phenobarbitone
B
Sodium valproate
C
Phenytoin
D
Primidone
High-Yield Explanation
Ans. is 'b' i.e., Sodium valproate o Most of the anticonvulsants are enzyme inducers except valproate which is an inhibitor. Note : Valprate is an enzyme inhibitor overall but it induces metabolism of carbamazepine: "Valproate and carbamazepine induce each other;s metabolism"

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