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Medicine General 2d7c184b

A 20 year old male presents with features of acute renal failure 5 days after an episode of diarrhea. Blood examination shows thrombocytopenia and Hb10 gm%. Likely cause is:

A
Haemolytic uremic syndrome
B
Hereditary spherocytosis
C
Haemolytic crises
D
Chronic glomerulonephritis
High-Yield Explanation
Answer is A (Hemolytic uremic syndrome): Patient presents with Renal failure 5 days after an episode of diarrhea. He has associated Anemia and Thrombocytopenia and thus qualifies the triad of HUS i.e. Anemia Thrombocytopenia Renal failure Remember In contrast to TTP, the HUS remains localized to the kidney, where hdyaline thrombi are seen in the afferent aerioles and glomerular capillaries. Such thrombi are not present in other vessels and neurologic symptoms, other than those associated with uremia are uncommon. DIC is not seen in both TTP & HUS

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