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Pediatrics General 2d3a942c

RDS in Neonate is due to deficiency of?

A
Sphingomyelin
B
Ceramide
C
Dipalmitoyl
D
All of above
High-Yield Explanation
Ans. is 'c' i.e., dipalmitoyl HMD (Respiratory distress syndrome) Primary seen in : PRETERM Baby of diabetic mother Multiple bih LSCS delivery Bih asphyxia Incidence in preterm inversely related to gestational age and bih weight. Primary cause - Surfactant deficiency leads to atelectatic lung. Major constituent of surfactant - la Dipalmitoyl phosphatidylcholine (lecithin) Phosphatidylglycerol A protein Cholesterol Synthesized and stored in type II alveolar cell. X-ray fine granuloreticular pattern with air bronchogram

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