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Psychiatry General 2d2cc185

Earliest symptom showing improvement from classical triad of Wernicke's incephalopathv. to thiamine therapy ?

A
Ataxia
B
Ophthalmoplegia
C
Confusion
D
All are equally responsive
High-Yield Explanation
Ans. is 'b' i.e., Ophthalmoplegia Response to thiamine treatment in Wernicke's encephalopathy Ocular symptoms :- Earliest to respond, ophthalmoplegia (ocular palsies) improves within hours of thiamine administration. However, horizontal nystagmus may persist. Ataxia :- Ataxia responds more slowly than ocular palsies and half the patients recover incompletely with a residual ataxia. Encephalopathy :- Confusion and other CNS symptoms improve more slowly. As the symptoms of encephalopathy improve, Korsakoff's syndrome may become apparent in some patients

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