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Biochemistry Enzymes 2ceb92a2

Which of the following is true about non-competitive inhibition?

A
Vmax |, no change in km
B
Vmax |, no change in km
C
Both Vmax and km |
D
Both Vmax and km |
High-Yield Explanation
Ans: a (Vmax |. no change in km) Ref: Vasudevan, 4th ed, p. 47; 5th ed,p. 46In non competitive inhibition there is no change in km value but Vmax |.Difference between competitive and non competitive inhibition Competitive inhibitionNon competitive inhibitionActing onActive siteMay or may notStructure of inhibitorSubstrate analogueUnrelated moleculeInhibition isExcess substrateKmVmaxReversibleInhibition relievedIncreasedNo changeIrreversibleNotNo changeDecreased

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