Third generation oral contraceptive pills containing norgestrel and gestodene along with estrogens :

Ans. is a i.e. Are more lipid friendly 3rd generation Oral contraceptive pill contain 3rd generation progestins such as : Desogestrel Gestodene Norgestimate Advantages of 3rd generation progestins are : Diminished adverse effects on lipid metabolism. Reliable monthly blood pattern The 3rd generation pills appear to carry higher risk of venous thrombosis but have lower risk of aerial thrombosis. Use of third generation progestins increase the risk of venous thromboembolism according to Shaw 14/e, p 209 whereas they have no effect on rate of thrombolism according to Leon Speroff 7/e, p 890. "Risks of aerial venous thrombosis are a consequence of the estrogen component of combination oral contraceptives." "There is no evidence that any oral contraceptive formulations that are approximately equivalent in estrogen and progesterin dosages are significantly different in the rate of breakthrough bleeding."