Allergic bronchopulmonary aspergillosis is characterized by all EXCEPT
High-Yield Explanation
(Not respond to steroid) (241-CMDT-10) (1259-H17th)* High doses of prednisone for at least 2 months is treatment of choice"* ABPA occurs in atopic asthmatic (particularly glucocorticoid dependent) individuals of age 20-40 years and non asthmatic individuals eg cystic fibrosisDiagnostic criteria for Bronchopulmoanry-AspergillosisPrimarySecondaryi. A clinical h/o Asthma**ii. Peripheral eosinophilea**iii. Immediate skin reactivity to aspergillus antigeniv. Precipitating Ab to aspergillus antigenv. |S.IgEvi. Pulmonary infiltrates* (transient or fixed)vii. Central bronchiectasis*** Identification of Asp.antigin sputum* H/o brown flesked sputum* Late skin reactivity to asp.antigen* Patients with corticosteroid dependent may benefited from itraconazole without toxicity* TRANSDATES PLEURAL EFFUSION (283-CMDT-10) causes CHF (90% of cases), cirrhosis with ascites, Nephrotic syndrome, peritoneal dialysis, Myxedema, Acute atlectasis, constrictive pericarditis, SVC obstruction, pulmonary embolism* Pleural tapping in mid-axillary line, muscle NOT pierced is Transversus thoracis (Sternocostalis)**