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Microbiology General 2c4ec272

True about cornebacterium diphtheriae is all except?

A
Deep invasion is not seen
B
Eleks test is done for toxigenicity
C
Metachromatic granules are seen
D
Toxigenicity is mediated by chromosomal change
High-Yield Explanation
Ans. is 'd' i.e., Toxigenicity is mediated by chromosomal change . This has been asked so many times in most of the examinations :? . Toxigenicity of diphtheria is not due to chromosomal change, it is phase mediated. About other options . Diphtheria is a toxemia, the bacilli remain confined to the site of entry, where they multiply and form toxin. . Elek's gel precipitation test is an in vitro test for toxigenicity. . Metachromatic granules (volutin or babes Ernest granules) are seen.

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