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Pathology General 2c44fd1a

Genomic imprinting is associated with-

A
Silencing of paternal chromosome
B
Silencing of maternal chgromosome
C
Angelman syndroma
D
All
High-Yield Explanation
Ans. is 'a' i.e., Silencing of paternal chromosome; 'b' i.e., Silencing of maternal chromosome; `c' i.e., Angelman syndroma Prader Willi Syndrome Deletion occurs exclusively on paternal chromosome 15 (deletion of band q 12 in long arm of chromosome 15) Features : Diminished fetal activity Hypotonia Obesity Mental retardation Sho stature Hypogonadotropic hypogonadism

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