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Pathology Lukemia 2c4171bf

AML - bad prognostic factor is?

A
Preceding MDS
B
Inv 16
C
Auer rods
D
Type M4
High-Yield Explanation
Ans. is 'a' i.e., Preceding MDS Prognostic factors in AMLo Age < 40 yearso Age < 2 years or > 55 yearso M2, M3, M4 forms of AMLo MO, M6, M7 forms of AMLo Blast cell with Auer rodso Complex karyotypeso TLC<25 x 109/LoTLC> 100 x 109/Lo t(15; 17), t (8;21), invl6o Deletions 5q, 7q (Monosomy 5 or 7)o Leukemia without preceeding MDSo AML with preceding MDS or anticancer drug exposure

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