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Pathology Haematology 2c3be2ab

Unconjugated hyperbilirubinemia with increased urobilinogen in -

A
Hemolytic anemia
B
Liver cirrhosis
C
Bile duct obstruction
D
Sclerosing cholangitis
High-Yield Explanation
In all uncomplicated hemolytic anemias,the excess serum bilirubin is unconjugated.The level of hyperbilirubinemia depends on functional capacity of liver & the rate of hemolysis. When liver is normal jaundice is rarely severe . Excessive bilirubin excreted by liver into GIT leads to increased formation and fecal excretion of urobilin ie increased urobilinogen Ref : Robbin 9/e pg 632

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