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Pathology Misc. (W.B.C) 2bfd5f69

"Smudge cells" in the peripheral smear are characteristic of

A
Chronic myelogenous leukemia
B
Chronic lymphocytic leukemia
C
Acute myelogenous leukemia
D
Acute lymphoblastic leukemia
High-Yield Explanation
Ans. (b) Chronic lymphocytic leukemia(Ref: Robbins 9th/pg 593; 8th/pg 603)"Smudge cells"Also called 'Basket cells', 'shadow cells of Gumprecht'Caused by decrease in VimentinMay predict good prognosisSeen mainly in CLL; Also have been reported in AML, CML, ALL & in normal peripheral smear, but rare;

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