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Pharmacology C.N.S 2be74c37

A patient with recent onset primary generalized epilepsy, develops drug reaction and skin rash and neutropenia due to phenytoin sodium. The most appropriate course of action is:

A
Shift to sodium valproate
B
Shift to clonazepam
C
Shift to ethosuximide
D
Restart phenytoin after 2 weeks
High-Yield Explanation
(Ref: Katzung, 14th ed. pg. 418-19; KDT 6th ed. pg. 405)Hypersensitivity reactions like rashes, DLE, lymphadenopathy and neutropenia require that phenytoin to be stopped.

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