Which one of the following preferentially activates plasminogen bound to fibrin and avoids the systemic lytic state -

Ans. is 'd' i.e., Alteplase o Alteplase, Reteplase and tenecteplase are recombinant t-PA. These are nonantigenic. They activate fibrin bound plasminogen only. o Streptokinase activates both free as well as fibrin bound plasminogen.