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Surgery General 2b5aa3cf

Prognosis of malignant melanoma depends upon: March 2011, March 2013

A
Grade of tumour
B
Age of the patient
C
Invasion of nearby nodes
D
Site of lesion
High-Yield Explanation
Ans. C: Invasion of nearby nodes The presence of lymph node metastases is the single most impoant prognostic index in melanoma, outweighing both tumour and host factors Melanoma: May be familial Originate from melanocytes Cutaneous melanoma arises from epidermal melanocytes Spread by the lymphatic channels or the bloodstream Lentigo maligna (least common) involves face commonly Superficial spreading is the MC type Nodular melanoma is the most malignant type

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