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Pediatrics General 2b303174

All of the following are good prognostic factors for childhood Acute Lymphoblastic Leukemia, except:

A
Hyperdiploidy
B
Female sex
C
Pre B cell ALL
D
t (12 : 21) translocation
High-Yield Explanation
Hyperdiploidy, Female sex and pre B cell ALL are associated with good prognosis. t (12 : 21) translocation may be associated with a poor prognosis and is the single answer of exclusion. Ref: Pediatric Oncology: A Comprehensive Guide By Paul Imbach, Thomas R. Kuhne, Robe Arceci, 2004, page 23.

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