Which of the following is not true about chromothrypsis?
High-Yield Explanation
Chromothrypsis Phenomenon by which up to thousands of clustered chromosomal rearrangements occur in a single event in localized and confined genomic regions Involved in cancer (1% -2%)and congenital diseases. Osteosarcomas and gliomas as well. Chromosome breaks occur within pa or across the entirety of a single chromosome or several chromosomes. Activate oncogenes and inactivate tumor suppressors, thereby expediting the process of carcinogenesis.