Full 2L QBank
Pharmacology Cardiovascular system 2a965423

Which of the following statin has the longest Half Life

A
Cerivastatin
B
Rosuvastatin
C
Atorvastatin
D
Simvastatin
High-Yield Explanation
Refer kDT 7/e 637 Rosuvastatin is primarily eliminated by excretion in the feces. The elimination half-lifeof rosuvastatin is approximately 19 hours.Rosuvastatin is not extensively metabolized; approximately 10% of a radiolabeled dose is recovered as metabolite. In contrast, the FDA suggests daytime administration for statins with longer half-lives (atorvastatin 14 hours, rosuvastatin 19 hours, and pravastatin 22 hours). Atorvastatin also has active metabolites withhalf-lives ranging from 20 to 30 hours, which may contribute to the fact that it can be taken at any time

Related Pharmacology MCQs

Practice 2,00,000+ NEET PG Questions Free

Timed mock tests, mistake queue analytics, audio lectures & zero attempt limits on i❤️Exams.

Start Free Mock Test Now