Glibenclamide is preferred over chlorpropamide in the treatment of diabetes mellitus because the latter is more likely to cause:

Chlorpropamide can cause: Jaundice Disulfiram like reaction Increase ADH Hyponatremia Increase Insulin Sulfonylureas Meglitinides 1st Generation : Chlorpropamide Tolbutamide - Nateglinide - Repaglinide 2nd generation: Glipizide Glicanide Glibenclamide