Which of the following statements about coagulation factor VII is not true?
High-Yield Explanation
Factor VII is a 56kd single chain, vitamin K dependent zymogen component of the extrinsic pathway of blood coagulation. So, its deficiency is associated with prolongation of PT not APTT. APTT is prolonged in case of deficiency of coagulation factors involved in intrinsic pathway. Ref: Autoantibodies By James B. Pete, Pages 179-80