65 years old male with history of acute onset of vomiting and weight loss was diagnosed to be stomach carcinoma. Whipple's procedure was planned. On preanesthetic evaluation it was found to have deranged kidney function. Inhalational agent of choice:-

Old age and long duration surgery desflurane is very ourable since minimal metabolism and fast recovery. Desflurane has a low blood solubility with a blood - gas paition coefficient of 0.45.The low solubility of desflurane in blood and body tissues causes a very rapid induction of and emergence from anesthesia