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Biochemistry Endocrinology 29ee17ec

Which of the following substances acts to increase the release of Ca2+ from endoplasmic reticulum?

A
Inositol triphosphate
B
Parathyroid hormone
C
1,25 dihydroxy cholecalciferol
D
Diacylglycerol
High-Yield Explanation
Ans. A. Inositol triphosphateInositol triphosphate (IP3 ) and diacylglycerol (DAG) are second messengers for G protein coupled receptors. IP3 stimulates release of calcium from endoplasmic reticulum. DAG activates protein kinase C.

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