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Medicine Haematology 29901fca

Laboratory evaluation for the differential diagnosis of chronic myeloproliferative disorders includes at thefollowingexcept.

A
Chromosomal evaluation
B
Bone marrow aspiration
C
Flow-cytometric analysis
D
Determination of red blood cell mass
High-Yield Explanation
<p>In chronic myeloproliferative disorder, chromosomal evaluation is needed to identify Philadelphia chromosome(CML) & trisomy 20(polycythemia vera). Bone marrow examination reveals hypercellularity with myeloid predominance in CML & erythroid hyperplasia in PV & hyperdiploid megakaryocytes in essential thrombocytopenia. Red cell mass will be increased in PV.</p><p>Reference :Harsh mohan textbook of pathology sixth edition pg no 358.</p>

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