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Pathology General 29406228

In an inflamatory response, which of the following are involved in the recognition of the microbes or damaged cells?

A
Toll-like receptors
B
NOD-Like receptors
C
Mannose-binding lectin protien
D
All of the above
High-Yield Explanation
Pattern recognition receptors are located in all the cellular compartments where pathogens may be present: plasma membrane receptors detect extracellular pathogens, endosomal receptors detect ingested microbes, and cytosolic receptors detect microbes in the cytoplasm. Several classes of these receptors have been identified: Toll-Like Receptors NOD-Like Receptors and the Inflammasome Other Receptors for Microbial Products: C-type lectin receptors (CLRs), RIG- like receptors, Mannose receptors. Reference-Robbins BASIC PATHOLOGY 10th edition pg-122,123

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