In an inflamatory response, which of the following are involved in the recognition of the microbes or damaged cells?
High-Yield Explanation
Pattern recognition receptors are located in all the cellular compartments where pathogens may be present: plasma membrane receptors detect extracellular pathogens, endosomal receptors detect ingested microbes, and cytosolic receptors detect microbes in the cytoplasm.
Several classes of these receptors have been identified:
Toll-Like Receptors
NOD-Like Receptors and the Inflammasome
Other Receptors for Microbial Products: C-type lectin receptors (CLRs), RIG- like receptors, Mannose receptors.
Reference-Robbins BASIC PATHOLOGY 10th edition pg-122,123