In which of the following disease is coicosteroids indicated ?

uses: asthma, multiple sclerosis, collgen vascular disease, autoimmune diseases,shock, COPD, uicaria, severe allergies, anaphylactic shock etc Glucocoicoid impair immunological competence. They suppress all type of hyoersensitation and allergic phenomenon. At high doses they interfere with immunological response. They are life saving in collagen diseases. Therapy is generally staed with high doses which are tappered to maintenence dose when remission occur. (REF.Essential of medical pharmacology K D TRIPATHI 6 Edition, Page No - 284)