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Pathology Urinary tract 291ce13b

IgA nephropathy has all the following characteristics except -

A
Hematuria
B
Hypeension
C
Nephritic syndrome
D
Thin basement membrane on renal biopsy
High-Yield Explanation
Histologically, the lesions in IgA nephropathy vary considerably. The glomeruli may be normal or may show mesangial widening and segmental inflammation confined to some glomeruli (focal proliferative GN); diffuse mesangial proliferation (mesangioproliferative GN); or (rarely) ove crescentic GN. The characteristic immunofluorescence picture is of mesangial deposition of IgA, often with C3 and properdin and smaller amounts of IgG or IgM. Ref: Robbins basic pathology 9th edition page 530

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