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Pharmacology A.N.S. 291b7388

b blocker/s which should be avoided in glaucoma is/are?

A
Pindolol
B
Carvedilol
C
Labetelol
D
All the above
High-Yield Explanation
Ans. is 'd' i.e., All the above * Beta blockers are used in the management of glaucoma. But certain ($- blockers with membrane stabilizing (Local anaesthetic) action should be avoided in glaucoma as these drugs possess Na+ channel blocking (local anaesthetic) activity.* Membrane stabilizing (Na+ channel blocking) activity contributes to antiarrhythmic action and should be avoided in glaucoma due to risk of corneal anaesthesia.* Such Drugs are:# Pindolol# Acebutolol# Carvedilol# Betaxolol# Propranolol# Metoprolol# Labetalol *Note: Propranolol and carvedilol have maximum membrane stabilizing (local anaesthetic) action.

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