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Physiology General 28def112

Binding of oxygen to myoglobin:

A
Is characterized by the sigmoidal saturation curve
B
Occurs at multiple sites
C
Is characterized by the sigmoid and multiple hyperbolic saturation curve
D
Is characterized by the hyperbolic saturation curve
High-Yield Explanation
Myoglobin molecule contains a single O2 binding site and thus the saturation process is characterized by a simple hyperbolic curve, in contrast to hemoglobin, sigmoid saturation curve of which shows positive cooperativity of multiple oxygen binding sites. Ref: Lippincott's Biochemistry, 5th Ed page 26

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