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Surgery Endocrinology and breast 28b22716

All of the following are true about medullary carcinoma of thyroid except

A
It is tumour arising from C cells derived from the neural crest
B
Secrete high levels of calcitonin
C
It is not dependent on TSH
D
Most cases are familial
High-Yield Explanation
MEDULLARY CARCINOMA It is an uncommon type it arises from the parafollicular C cells which is derived from ultimobranchial body (neural crest) blood level of calcitonin is a tumour marker it is not dependant on TSH Most cases are sporadic and a small amount is familial ref ;(page no;486) 5th edition of SRB&;S Manual of SURGERY

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