Physiology Blood: RBCs, Anemia, and Polycythemia 287b713b 2,3 DPG causes - A Decrease binding of O2 and hemoglobin B Increased acidity in RBC C Decreased acidity in RBC D Lysis of RBC High-Yield Explanation Ans. is 'a' i.e., Decrease binding of O2 and hemoglobin