A female paitent of 30 years developed a feature of septicemia. Shock in form of hypotension and low urine output. She was being T/t for colonic necrosis. What will be the m/n -

Treatment of septic shock First line of treatment : Aggressive volume expansion with crystalloid solution and restoration of aerial Oxygenation with inspired oxygen and frequently with mechanical ventilation are the highest priorities Second line: Inotropic suppo with dopamine, norepinephrine or vasopressin in the presence of hypotension or dobutamine if aerial pressure is normal High dose activated protein C (APX) provides a survival benefit in patients with severe sepsis and septic shock Plasma expanders are useful as septic shock is associated with peripheral vasodilation causing Reactive hypovolemia Antibiotics and surgical Debridement or drainage to control infection Ref: Sabiston 20th edition Pgno :554