Jod-Basedow phenomenon refers to which of the following?
High-Yield Explanation
It is named for Karl Adolph von Basedow, a German physician and the German word for iodine, "jod". It is the opposite of the Wolff-Chaikoff effect. Amiodarone can cause thyrotoxicosis that may be caused by either a Jod-Basedow effect from the iodine load, in the setting of MNG or incipient Graves' disease. Ref: Harrisons Principles of Internal Medicine, 18th Edition, Table 341-6, Causes of Thyrotoxicosis, Pages 2922, 2930-31.