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Medicine Renal Tubular Disease 28066514

True about Nephrogenic diabetes insipidus is?

A
Renal tubule unresponsive ness to ADH
B
There is central decrease in secretion of ADH
C
Serum Na is low
D
The urine osmolarity is increased after ADH administration
High-Yield Explanation
ANSWER: (A) Renal tubule unresponsiveness to ADHREF: Harrisons medicine 17th ed 2219In Nephrogenic diabetes insipidus the tubules are unresponsive to the ADH and it could be due to acquired, genetic, drugsParametersPsychogenicpolydipsiaDiabetesinsipidusNephrogenic DIOsmotic diuresisSerum NaN or decIncreaseIncreaseN or incPlasma osmN or decIncreaseIncreaseN or incUrine osmDecdecreasedecreaseIncreasePlasma ADHDecdecreaseIncreaseIncreaseUrine osm after ADHIncreaseincreasenilSlight increase
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