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Anaesthesia Regional anaesthesia 279b0697

All the following statements about Epinephrine used as an adjuvant are true Except

A
Extends block duration, limits systemic uptake, supplements analgesic effect, and acts as an indicator of intravascular injection
B
Can cause toxicity to peripheral nerves in patients with diabetes or chemotherapy
C
Local anaesthetics and epinephrine have no effect on peripheral nerve blood flow
D
Can aggravate local anaesthetic-induced neuraxial or peripheral nerve injury
High-Yield Explanation
Local anesthetics and epinephrine significantly reduce peripheral nerve blood flow. Low-dosage epidural usage results in uptake and decreases systemic vascular resistance and increases cardiac output.

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