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Medicine General 2795270b

A 45-year old chronic alcoholic patient developed ascites and decreased libido. Physical examination revealed mild enlargement of the breasts and atrophy of testes. A liver biopsy was done. All of the followings are probable findings seen in histopathologic examination, EXCEPT:

A
Complete disruption of hepatic lobular architecture
B
Bands of fibrosis
C
Necrosis and infiltration of neutrophils within hepatic lobules
D
Regenerating lobules
High-Yield Explanation
Chronic alcohol intake may give rise to cirrhosis of the liver in the long run. Cirrhosis of the liver is featured by destruction of hepatic lobules, regeneration of hepatic lobules, formation of fibrotic bands, and infiltration of lymphocytes within fibrous bands. Stasis of bile and proliferation of bile ductule are also seen. Necrosis and infiltration of neutrophils and lymphocytes of hepatic lobules are seen in chronic active hepatitis. Ref: Bacon B.R. (2012). Chapter 308. Cirrhosis and Its Complications. In D.L. Longo, A.S. Fauci, D.L. Kasper, S.L. Hauser, J.L. Jameson, J. Loscalzo (Eds),Harrison's Principles of Internal Medicine, 18e.

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