In Medical termination of pregnancy, according to FDA, Misoprostol is given after how many hours of Mifepristone?

FDA approved protocol - (Original protocol) 600 mg of mifepristone (i.e., 3 tablets) given orally on day 1 followed 2 days (48 hours) later by oral misoprostol 400 tig (2 tablets) on day 3. The treatment should be staed no more than 48 days from the sta of the last menstrual period. But according to the recent protocol 200 mg of mifepristone (it is as effective as 600 mg of mifepristone) is given orally on Day 1 followed 2 days (48 hours) later by vaginal misoprostol 800 pg. This regime provides highest efficacy within 63 days of amenorrhea. Ref : Dutta book of obstetrics 8th Ed