Peripoal fatty infiltration of liver is seen with

MORPHOLOGIC FEATURES. The pathologic features are common to both HBV and HCV infection and include the following lesions 1.Piecemeal necrosis. Piecemeal necrosis is defined as peripoal destruction of hepatocytes at the limiting plate (piecemeal = piece by piece). Its features in chronic hepatitis are as under: i)Necrosed hepatocytes at the limiting plate in peripoal zone. ii)Interface hepatitis due to expanded poal tract by infiltration of lymphocytes, plasma cells and macrophages. iii)Expanded poal tracts are often associated with proliferating bile ductules as a response to liver cell injury. 2.Poal tract lesions. All forms of chronic hepatitis are characterised by variable degree of changes in the poal tract. i)Inflammatory cell infiltration by lymphocytes, plasma cells and macrophages (triaditis). ii)Proliferated bile ductules in the expanded poal tracts. iii)Additionally, chronic hepatitis C may show lymphoid aggregates or follicles with reactive germinal centre TEXT BOOK OF HARSH MOHAN SIXTH EDITION PAGE.611 IMAGE REF: TEXTBOOK OF HARSH MOHAN SIXTH EDITION FIG:21-13 PAGE 612