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Surgery Plastic & Reconstructive Surgery 260f1f42

A 70 year old male known case of a certain malignancy presents with elevated erythropoietin levels and PCV of 52%. Most likely tumour is -

A
Renal Cell Carcinoma
B
Medullary thyroid carcinoma
C
Gastric Carcinoma
D
Colorectal CA
High-Yield Explanation
Ans. is 'a' i.e., Renal Cell Carcinoma Paraneoplastic syndromes in RCCParaneoplastic syndormesi) Fever of unknown originii) Anemiaiii) Erythrocytosis (d/t secretion of erythropoietin by RCC) (but anemia is a more common finding)iv) Hypertensionv) Abnormal liver function (Stauffers syndrome ie non metastatic hepatic dysfunction)vi) Hypercalcemiavii) Neuromyopathyviii) Amyloidosisix) Increased ESR (MC paraneoplastic syndrome)x) Dysfibrogenemiaxi) Galactorrhoeaxii) Feminization and masculanization

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