Christmas disease is treated by

Fresh frozen contains all the coagulation factors except platelets. Also erythrocytes and leukocytes are absent in it. The specific treatment is with factor9 concentrate. The new extended half life recombinant factor 9 products made by Fc fusion, albumin fusion and pegylation offer the possibility of prophylaxis on a once-weekly or even two-weekly schedule. Reference : Davidson, 23rd Edition, page no : 974.