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Pathology Cellular Pathology 25ed0646

Change seen in mitochondria due to aging is?

A
Decrease in size & increase in number
B
Decrease in number & increase in size
C
Decrease in size and number both
D
Increase in size and number both
High-Yield Explanation
Ans. is 'c' i.e., Decrease in size and number both Morphological changes associated with agingCellular changesDecrease in cell size and numberDecreased in size and number of mitochondria Detachment of ribosomes from ERIncreased number of phagolysosomal vacuolesDefective DNA repairNon-enzymatic glycosylation ofprotienConnective tissue changesThere is loss of elasticity (wrinkling of skin| BP due to decreased elasticity of artery)Ground glass substance changes (cataract)Cartilage and bone changes (osteoarthritis, osteoporosis)Decreased immunityDecreased T cells, B cells, plasma cells and antibodies

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