The type of mammary ductal carcinoma in situ (DCIS) most likely to result in a palpable abnormality in the breast is -

Carcinoma of the breast is divided into : Carcinoma in situ → neoplastic cells is limited to ducts and lobules by the basement membrane. Invasive carcinoma (infiltrating carcinoma) → cells invade beyond the basement membrane. Caricnoma in situ : It is of two types A. Ductal carcinoma insitu (DCIS, intraductal carinoma ) Most frequently present as manzmographic calcification. Rarely palpable mass may also occur in comedocarcinoma. DCTS is of two types - i. Comedocarcinoma ii. Noncomedo DCTS → Solid, cribriform, papillary or micropapillary B. Lubular carcinoma in Situ (LCIS) Always an incidental finding in a biopsy performed for another reason. LCIS is not associated with calcification → Therefore, it remains infrequent with or without mammography (in contrast to DCIS) Frequently multicentric and bilateral Signet ring cells are common.