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Medicine All India exam 249bd116

Pseudoporphyria can be induced by all except

A
Methotrexate
B
Nalidixic acid
C
Naproxen
D
Isotretinoin
High-Yield Explanation
Pseudoporphyria is generally due to drugs or other agents which interact with sunlight to cause a phototoxic reaction in the skin. These include:Non-steroidal anti-inflammatory drugs e.g. naproxenAntibiotics - doxycycline, nalidixic acidDiuretics - chlohalidone, bumetanide, furosemide (frusemide) and hydrochlorothiazide/triamtereneRetinoids - isotretinoin, etretinate, acitretinOral contraceptives(ref:Harrison's 18/e p414,415)

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