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Pathology Genetics 249864f2

Karyotyping is done in which phase of cell cycle:

A
Anaphase
B
Metaphase
C
Telophase
D
S phase
High-Yield Explanation
Ans. (b) Metaphase(Ref: Robbins 9th/pg 158; 8th/pg 159)In KaryotypeChromosomes are examined after arresting dividing cells in metaphase with mitotic spindle inhibitors (e.g. N-diacetyl-N-methylcolchicine), followed by stainingResolution of Karyotyping: 2 to 5 million base pairs Q

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