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Biochemistry General 245c0e01

All of the following are the reasons for impaired absorption of calcium except:

A
Inositol hexaphosphate in cereals
B
High intake of oxalate
C
High concentrations of fatty acids in the intestinal lumen
D
Decreased iron intake
High-Yield Explanation
Phytic acid (inositol hexaphosphate) in cereals binds calcium in the intestinal lumen, preventing its absorption. Other minerals, including zinc, are also chelated by phytate. This is mainly a problem among people who consume large amounts of  unleavened  whole-wheat  products;  yeast  contains  an enzyme, phytase, that dephosphorylates phytate, so rendering it inactive. High concentrations of fatty acids in the intestinal lumen, as a result of impaired fat absorption, can also reduce calcium absorption by forming insoluble calcium salts; a high intake of oxalate can sometimes cause deficiency since calcium oxalate is insoluble. HARPERS ILLUSTRATED BIOCHEMISTRY30th, Page No: 541

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