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Gynaecology & Obstetrics General 244adc66

Women undergoing infertility treatment are advised to avoid NSAIDs in preovulatory period because

A
Prostaglandins contribute to ovulation
B
NSAIDs inhibit LH surge
C
NSAIDs cause premature rupture of follicle
D
NSAIDs like aspirin cause endometrial shedding.
High-Yield Explanation
Prostaglandin stimulates smooth muscle contraction in ovary, contributing to ovulation.  prostaglandin synthetase inhibitors if taken in pre ovulatory period can cause luteinized unruptured follicle syndrome (LUFS).

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