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Pathology Misc. 2441e7bf

All of the following is associated with gastric carcinoma EXCEPT

A
H. pylori infection
B
Smoking
C
Nitrates
D
Blood group B
High-Yield Explanation
(D) Blood group B FACTORS ASSOCIATED WITH INCREASED INCIDENCE OF GASTRIC CARCINOMAEnvironmental FactorsHost FactorsGenetic* Infection by H. pylori* Present in most cases of intestinal-type carcinoma* Diet* Nitrites derived from nitrates (water, preserved food)* Smoked and salted foods, pickled vegetables* Lack of fresh fruit and vegetables* Low socioeconomic status* Cigarette smoking* Chronic gastritis* Hypochlorhydria: favors colonization with Helicobacter pylori* Intestinal metaplasia is a precursor lesion* Infection by H. pylori* Present in most cases of intestinal-type carcinoma* Partial gastrectomy* Favors reflux of bilious, alkaline intestinal fluid* Gastric adenomas* 40% harbor cancer at time of diagnosis* 30% have adjacent cancer at time of diagnosis* Barrett esophagus* Increased risk of gastroesophageal junction tumors* Slightly increased risk with blood group A* Family history of gastric cancer* Hereditary nonpolyposis colon cancer syndrome> Individuals with blood group 'A' have a higher incidence of gastric cancer than persons with blood group 'O'

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