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Social & Preventive Medicine General 241b129b

True about measles vaccine ?

A
Killed vaccine
B
In epidemic vaccine is given at 9 months of age
C
Can cause TSS
D
Duration of protection is 5-10 years
High-Yield Explanation
Ans. is 'c' i.e., Can cause TSS Measles vaccine : Type: Live attenuated, lyophilized (Freeze dried) vaccine Strains used: Edmonston Zagreb Strain (Most Common) Schwaz Strain Moraten Strain Dose: 0.5 ml Route: Subcutaneous Site: Antero-lateral aspect of thigh (middle one-third) Age of administration in National Immunisation schedule (India): 9 months (can be lowered to 6-9 months in epidemics & malnutrition) Diluent for Reconstitution: Distilled Water or sterile water Use within 1 hr after reconstitution with diluent Measles (& MMR) vaccine can lead to Toxic Shock Syndrome Measles vaccine is contraindicated in pregnancy Cold chain Temperature for storage: +2 to +8 degree C Protective efficacy: > 95% Duration of Protection: Life long IP of vaccine induced measles: 7 days Measles immunoglobulin is also available for post exposure prophylaxis. The best age for measles vaccination is 9 months. The age can be lowered to 6 months if there is measles outbreak in the community. For infants immunized between 6 months and 9 months of age, a second dose should be administered as soon as possible after the child reaches the age of 9 months provided that at least 4 weeks have elapsed since the last dose.

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